The average train between Brescia and Palermo takes 22h 58m and the fastest train takes 16h 34m. The train service runs several times per day from Brescia to Palermo. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run twice daily between Brescia and Palermo. The earliest departure is at 6:47 AM in the morning, and the last departure from Brescia is at 5:29 PM which arrives into Palermo at 7:29 PM. All services require a transfer at Roma Termini and take an average of 22h 58m. The schedules shown below are for the next available departures.
Arrives next day


21h 29m • 2 changes
Arrives next day


26h • 2 changes
Arrives next day


17h 15m • 2 changes
Arrives next day


25h 56m • 2 changes
Arrives next day


21h 29m • 2 changes
Arrives next day


26h • 2 changes
Want to know about travelling from Brescia to Palermo? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Brescia to Palermo. However, there are services departing from Brescia station and arriving at Palermo station via Roma Termini. The journey, including transfers, takes approximately 22h 58m.
Brescia to Palermo train services, operated by ItaloTreno, depart from Brescia station.
Brescia to Palermo train services, operated by ItaloTreno, arrive at Palermo Centrale station.
Book your Brescia to Palermo train tickets online with ItaloTreno, Trenitalia Intercity and Trenitalia.
The distance between Brescia and Palermo is 862.7 km. The road distance is 1,403 km.
You can take a train from Brescia to Palermo Notarbartolo via Roma Termini and Palermo Centrale in around 17h 9m.