The average train between Brindisi and Ascoli Piceno takes 6h 36m and the fastest train takes 5h 15m. The train service runs several times per day from Brindisi to Ascoli Piceno. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run every 4 hours between Brindisi and Ascoli Piceno. The earliest departure is at 4:00 AM at night, and the last departure from Brindisi is at 10:24 PM which arrives into Ascoli Piceno at 10:25 AM. All services require a transfer at San Benedetto Tronto and take an average of 6h 36m. The schedules shown below are for the next available departures.


6h 26m • 2 changes


5h 55m • 2 changes


6h 3m • 2 changes


7h 29m • 2 changes


6h 26m • 2 changes


5h 55m • 2 changes


6h 3m • 2 changes


7h 29m • 2 changes


6h 26m • 2 changes


5h 55m • 2 changes


6h 3m • 2 changes


7h 29m • 2 changes


6h 22m • 2 changes


5h 55m • 2 changes


6h 3m • 2 changes


5h 52m • 2 changes


5h 15m • 2 changes


6h 38m • 2 changes


6h 46m • 2 changes


6h 50m • 2 changes


6h 22m • 2 changes


5h 55m • 2 changes


6h 3m • 2 changes


7h 26m • 2 changes
Want to know about travelling from Brindisi to Ascoli Piceno? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Brindisi to Ascoli Piceno. However, there are services departing from Brindisi station and arriving at Ascoli Piceno station via San Benedetto Tronto. The journey, including transfers, takes approximately 6h 36m.
Brindisi to Ascoli Piceno train services, operated by Trenitalia, depart from Brindisi station.
Brindisi to Ascoli Piceno train services, operated by Trenitalia, arrive at San Benedetto Tronto station.
Book your Brindisi to Ascoli Piceno train tickets online with Trenitalia, Trenitalia Frecce and Trenitalia Intercity.
The distance between Brindisi and Ascoli Piceno is 438.1 km. The road distance is 501 km.
Trenitalia Frecce operates a train from Brindisi to San Benedetto Tronto 5 times a day. Tickets cost €70–140 and the journey takes 4h 10m. Trenitalia Intercity also services this route every 3 hours.