The average train between Brindisi and Cassino takes 7h 48m and the fastest train takes 6h. The train service runs several times per day from Brindisi to Cassino. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run 4 times a day between Brindisi and Cassino. The earliest departure is at 7:29 AM in the morning, and the last departure from Brindisi is at 5:29 PM which arrives into Cassino at 5:30 AM. All services require a transfer, and take on average 7h 48m. The schedules shown below are for the next available departures.

6h 45m • 1 change
6h 16m • 1 change
6h 26m • 1 changeArrives next day

12h 1m • 1 change
6h 45m • 1 change
6h 16m • 1 change
6h 26m • 1 changeArrives next day

12h 1m • 1 change
6h 45m • 1 change
6h 16m • 1 change
6h 26m • 1 changeArrives next day

12h 1m • 1 change
6h 45m • 1 change
6h 42m • 1 change
6h 16m • 1 change
7h 11m • 1 changeWant to know about travelling from Brindisi to Cassino? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Brindisi to Cassino. However, there are services departing from Brindisi station and arriving at Cassino station via Caserta. The journey, including transfers, takes approximately 7h 48m.
Brindisi to Cassino train services, operated by Trenitalia Frecce, depart from Brindisi station.
Brindisi to Cassino train services, operated by Trenitalia Frecce, arrive at Cassino station.
Book your Brindisi to Cassino train tickets online with Trenitalia Frecce, Trenitalia and Trenitalia Intercity.
The distance between Brindisi and Cassino is 357.2 km. The road distance is 469 km.
You can take a train from Brindisi to Cassino via Caserta in around 6h 6m.