The average train between Brindisi and Prague takes 29h 20m and the fastest train takes 26h. The train service runs several times per day from Brindisi to Prague. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run twice daily between Brindisi and Prague. The earliest departure is at 7:23 AM in the morning, and the last departure from Brindisi is at 1:18 PM which arrives into Prague at 9:58 PM. All services require a transfer at Venezia Mestre and take an average of 29h 20m. The schedules shown below are for the next available departures.
Arrives next day


26h • 2 changes
Arrives next day


32h 40m • 2 changes
Arrives next day


26h • 2 changes
Arrives next day


32h 40m • 2 changes
Arrives next day


26h • 2 changes
Arrives next day


32h 40m • 2 changes
Want to know about travelling from Brindisi to Prague? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Brindisi to Prague. However, there are services departing from Brindisi station and arriving at Prague station via Venezia Mestre. The journey, including transfers, takes approximately 29h 20m.
Brindisi to Prague train services, operated by Trenitalia Frecce, depart from Brindisi station.
Brindisi to Prague train services, operated by Trenitalia Frecce, arrive at Praha Hlavni Nadrazi station.
Book your Brindisi to Prague train tickets online with Trenitalia Frecce, Railjet and RegioJet.
The distance between Brindisi and Prague is 1,086.4 km. The road distance is 1,986 km.
You can take a train from Brindisi to Praha Hlavni Nadrazi via Venezia Mestre and Wien Hbf in around 21h 15m.