The average train between Brindisi and Sezze takes 6h 58m and the fastest train takes 6h 30m. The train service runs several times per day from Brindisi to Sezze. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run 5 times a day between Brindisi and Sezze. The earliest departure is at 6:29 AM in the morning, and the last departure from Brindisi is at 5:29 PM which arrives into Sezze at 12:01 AM. All services require a transfer, and take on average 6h 58m. The schedules shown below are for the next available departures.

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7h 22m • 1 changeWant to know about travelling from Brindisi to Sezze? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Brindisi to Sezze. However, there are services departing from Brindisi station and arriving at Sezze station via Roma Termini. The journey, including transfers, takes approximately 6h 58m.
Brindisi to Sezze train services, operated by Trenitalia Frecce, depart from Brindisi station.
Brindisi to Sezze train services, operated by Trenitalia Frecce, arrive at Sezze Romano station.
Book your Brindisi to Sezze train tickets online with Trenitalia Frecce and Trenitalia.
The distance between Brindisi and Sezze is 419.8 km. The road distance is 658 km.
You can take a train from Brindisi to Sezze Romano via Roma Termini in around 6h 44m.