The average train between Brno and Brussels takes 17h 16m and the fastest train takes 14h 8m. The train service runs several times per day from Brno to Brussels. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run 5 times a day between Brno and Brussels. The earliest departure is at 7:18 AM in the morning, and the last departure from Brno is at 10:18 PM which arrives into Brussels at 5:26 PM. All services require a transfer at Wien Hbf and take an average of 17h 16m. The schedules shown below are for the next available departures.




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18h 8m • 4 changesWant to know about travelling from Brno to Brussels? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Brno to Brussels. However, there are services departing from Brno station and arriving at Brussels station via Wien Hbf. The journey, including transfers, takes approximately 17h 16m.
Brno to Brussels train services, operated by České dráhy (ČD), depart from Brno Hlavni Nadrazi station.
Brno to Brussels train services, operated by České dráhy (ČD), arrive at Brussels-Nord station.
Book your Brno to Brussels train tickets online with České dráhy (ČD), Railjet and 9 other operators.
The distance between Brno and Brussels is 893.8 km. The road distance is 1,397 km.
You can take a train from Brno Hlavni Nadrazi to Brussels-Nord via Wien Hbf, Salzburg Hbf, Salzburg Hauptbahnhof, München Hbf, and Frankfurt in around 13h 23m.