The average train between Brno and Karlsruhe takes 11h 13m and the fastest train takes 9h 35m. The train service runs several times per day from Brno to Karlsruhe. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run 5 times a day between Brno and Karlsruhe. The earliest departure is at 7:18 AM in the morning, and the last departure from Brno is at 10:18 PM which arrives into Karlsruhe at 12:53 PM. All services require a transfer at Wien Hbf and take an average of 11h 13m. The schedules shown below are for the next available departures.


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11h 6m • 2 changesWant to know about travelling from Brno to Karlsruhe? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Brno to Karlsruhe. However, there are services departing from Brno Hlavni Nadrazi station and arriving at Karlsruhe Hauptbahnhof station via Wien Hbf station and Nuernberg Hbf station. The journey, including transfers, takes approximately 11h 13m.
Brno to Karlsruhe train services, operated by České dráhy (ČD), depart from Brno Hlavni Nadrazi station.
Brno to Karlsruhe train services, operated by Deutsche Bahn Intercity (DB IC), arrive at Karlsruhe Hauptbahnhof station.
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The distance between Brno and Karlsruhe is 597.3 km. The road distance is 726 km.
You can take a train from Brno Hlavni Nadrazi to Karlsruhe Hauptbahnhof via Wien Hbf, Nuernberg Hbf, and Nürnberg Hbf in around 11h.