The average train between Brno and Nové Mesto takes 2h 25m and the fastest train takes 1h 53m. The train service runs several times per day from Brno to Nové Mesto. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run every 4 hours between Brno and Nové Mesto. The earliest departure is at 8:22 AM in the morning, and the last departure from Brno is at 10:22 PM which arrives into Nové Mesto at 4:35 AM. All services require a transfer at Bratislava hlavná stanica and take an average of 2h 25m. The schedules shown below are for the next available departures.

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Want to know about travelling from Brno to Nové Mesto? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Brno to Nové Mesto. However, there are services departing from Brno station and arriving at Nové Mesto station via Bratislava hlavná stanica. The journey, including transfers, takes approximately 2h 25m.
Brno to Nové Mesto train services, operated by ÖBB EuroCity, depart from Brno hl.n. station.
Brno to Nové Mesto train services, operated by ÖBB EuroCity, arrive at Bratislava hlavná stanica station.
Book your Brno to Nové Mesto train tickets online with ÖBB EuroCity and Slovakia Public Transport.
The distance between Brno and Nové Mesto is 120.8 km. The road distance is 145 km.
ÖBB EuroCity operates a train from Brno hl.n. to Bratislava hlavná stanica every 4 hours. Tickets cost €30–55 and the journey takes 1h 40m. RegioJet also services this route 4 times a day.