The average train between Brussels Airport (BRU) and Lyon takes 4h 51m and the fastest train takes 4h 29m. The train service runs several times per day from Brussels Airport (BRU) to Lyon. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run every 4 hours between Brussels Airport (BRU) and Lyon. The earliest departure is at 12:30 AM at night, and the last departure from Brussels Airport (BRU) is at 11:59 PM which arrives into Lyon at 10:28 AM. All services require a transfer, and take on average 4h 51m. The schedules shown below are for the next available departures.

4h 36m • 1 change

4h 35m • 1 change

4h 38m • 1 change

4h 35m • 1 change

9h 58m • 1 change

4h 47m • 1 change

4h 36m • 1 change

4h 35m • 1 change

4h 38m • 1 change

4h 31m • 1 change

4h 30m • 1 change

4h 29m • 1 change

4h 38m • 1 change

4h 31m • 1 change

4h 30m • 1 change

4h 29m • 1 change

4h 38m • 1 change

4h 31m • 1 change

4h 30m • 1 change

4h 29m • 1 change

4h 38m • 1 change

4h 31m • 1 change

4h 30m • 1 change

4h 29m • 1 change
Want to know about travelling from Brussels Airport (BRU) to Lyon? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Brussels Airport (BRU) to Lyon. However, there are services departing from Brussels Airport (BRU) station and arriving at Lyon station via Lyon Part Dieu. The journey, including transfers, takes approximately 4h 51m.
Brussels Airport (BRU) to Lyon train services, operated by Belgian Railways (NMBS/SNCB), depart from Brussel-Zuid / Bruxelles-Midi station.
Brussels Airport (BRU) to Lyon train services, operated by Belgian Railways (NMBS/SNCB), arrive at Lyon Part Dieu station.
Book your Brussels Airport (BRU) to Lyon train tickets online with Belgian Railways (NMBS/SNCB) and TGV inOui.
The distance between Brussels Airport (BRU) and Lyon is 573.2 km. The road distance is 766 km.
TGV inOui operates a train from Brussel-Zuid / Bruxelles-Midi to Lyon Part Dieu every 2 hours. Tickets cost €150–250 and the journey takes 3h 52m.