The average train between Brussels Central Station and Mainz takes 3h 28m and the fastest train takes 3h 19m. The train service runs several times per day from Brussels Central Station to Mainz. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run every 3 hours between Brussels Central Station and Mainz. The earliest departure is at 6:14 AM in the morning, and the last departure from Brussels Central Station is at 8:25 PM which arrives into Mainz at 12:22 AM. All services require a transfer at Brussels-Nord and take an average of 3h 28m. The schedules shown below are for the next available departures.


3h 30m • 2 changes


3h 22m • 2 changes


3h 22m • 2 changes


3h 22m • 2 changes


3h 30m • 2 changes


3h 22m • 2 changes


3h 22m • 2 changes


3h 22m • 2 changes


3h 22m • 2 changes


3h 19m • 2 changes


3h 19m • 2 changes


3h 19m • 2 changes


3h 22m • 2 changes


3h 19m • 2 changes


3h 19m • 2 changes


3h 19m • 2 changes


3h 22m • 2 changes


3h 19m • 2 changes


3h 19m • 2 changes


3h 19m • 2 changes


3h 22m • 2 changes


3h 19m • 2 changes


3h 19m • 2 changes


3h 19m • 2 changes
Want to know about travelling from Brussels Central Station to Mainz? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Brussels Central Station to Mainz. However, there are services departing from Brussels Central Station station and arriving at Mainz station via Frankfurt(M) Flughafen Fernbf. The journey, including transfers, takes approximately 3h 28m.
Brussels Central Station to Mainz train services, operated by Belgian Railways (NMBS/SNCB), depart from Brussels-Nord station.
Brussels Central Station to Mainz train services, operated by Belgian Railways (NMBS/SNCB), arrive at Frankfurt(M) Flughafen Fernbf station.
Book your Brussels Central Station to Mainz train tickets online with Belgian Railways (NMBS/SNCB), Deutsche Bahn Intercity (DB IC) and 2 other operators.
The distance between Brussels Central Station and Mainz is 293.9 km. The road distance is 413 km.
Deutsche Bahn Intercity (DB IC) operates a train from Brussels-Nord to Frankfurt(M) Flughafen Fernbf hourly. Tickets cost €70–300 and the journey takes 2h 39m. Belgian Railways (NMBS/SNCB) also services this route once a week.