The average train between Brussels and Domodossola takes 13h 11m and the fastest train takes 8h 57m. The train service runs several times per day from Brussels to Domodossola. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run twice daily between Brussels and Domodossola. The earliest departure is at 6:03 AM in the morning, and the last departure from Brussels is at 9:16 PM which arrives into Domodossola at 4:10 PM. All services require a transfer at Paris Nord and take an average of 13h 11m. The schedules shown below are for the next available departures.



10h 7m • 3 changes



9h 57m • 3 changes
Arrives next day



13h 57m • 3 changes
Arrives next day



18h 54m • 3 changes



9h 57m • 3 changes
Arrives next day



13h 57m • 3 changes
Arrives next day



18h 54m • 3 changes



10h 7m • 3 changes



9h 57m • 3 changes
Arrives next day



13h 57m • 3 changes
Arrives next day



18h 54m • 3 changes
Want to know about travelling from Brussels to Domodossola? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Brussels to Domodossola. However, there are services departing from Brussels station and arriving at Domodossola station via Paris Nord. The journey, including transfers, takes approximately 13h 11m.
Brussels to Domodossola train services, operated by Eurostar, depart from Brussel-Zuid / Bruxelles-Midi station.
Brussels to Domodossola train services, operated by Eurostar, arrive at Domodossola station.
Book your Brussels to Domodossola train tickets online with Eurostar, Société Nationale des Chemins de fer Français (SNCF) and 2 other operators.
The distance between Brussels and Domodossola is 601.1 km. The road distance is 1,054 km.
You can take a train from Brussel-Zuid / Bruxelles-Midi to Domodossola via Paris Nord, Paris Gare De Lyon, and Genève in around 9h 16m.