The average train between Brussels and Isernia takes 24h 34m and the fastest train takes 22h 10m. The train service runs several times per day from Brussels to Isernia. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run 3 times a day between Brussels and Isernia. The earliest departure is at 7:02 AM in the morning, and the last departure from Brussels is at 9:29 PM which arrives into Isernia at 7:55 PM. All services require a transfer at Paris Nord and take an average of 24h 34m. The schedules shown below are for the next available departures.
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22h 10m • 5 changes
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26h 10m • 5 changes
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24h 57m • 5 changes
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22h 10m • 5 changes
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26h 10m • 5 changes
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24h 57m • 5 changes
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22h 10m • 5 changes
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26h 10m • 5 changes
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24h 57m • 5 changes
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22h 10m • 5 changes
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26h 10m • 5 changes
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24h 57m • 5 changes
Want to know about travelling from Brussels to Isernia? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Brussels to Isernia. However, there are services departing from Brussels station and arriving at Isernia station via Paris Nord. The journey, including transfers, takes approximately 24h 34m.
Brussels to Isernia train services, operated by Eurostar, depart from Brussel-Zuid / Bruxelles-Midi station.
Brussels to Isernia train services, operated by Eurostar, arrive at Isernia station.
Book your Brussels to Isernia train tickets online with Eurostar, Société Nationale des Chemins de fer Français (SNCF) and 4 other operators.
The distance between Brussels and Isernia is 1,277.2 km. The road distance is 1,915 km.
You can take a train from Brussel-Zuid / Bruxelles-Midi to Isernia via Paris Nord, Paris Gare De Lyon, Torino Porta Susa, Milano Rogoredo, and Roma Termini in around 15h 28m.