The average train between Brussels and Isernia takes 24h 31m and the fastest train takes 21h 45m. The train service runs several times per day from Brussels to Isernia. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run twice daily between Brussels and Isernia. The earliest departure is at 10:42 AM in the morning, and the last departure from Brussels is at 9:16 PM which arrives into Isernia at 10:26 PM. All services require a transfer at Paris Nord and take an average of 24h 31m. The schedules shown below are for the next available departures.
Want to know about travelling from Brussels to Isernia? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Brussels to Isernia. However, there are services departing from Brussels station and arriving at Isernia station via Paris Nord. The journey, including transfers, takes approximately 24h 31m.
Brussels to Isernia train services, operated by Eurostar, depart from Brussel-Zuid / Bruxelles-Midi station.
Brussels to Isernia train services, operated by Eurostar, arrive at Isernia station.
Book your Brussels to Isernia train tickets online with Eurostar, Société Nationale des Chemins de fer Français (SNCF) and 4 other operators.
The distance between Brussels and Isernia is 1,277.2 km. The road distance is 1,919 km.
You can take a train from Brussel-Zuid / Bruxelles-Midi to Isernia via Paris Nord, Paris Gare De Lyon, Torino Porta Susa, and Roma Termini in around 16h 31m.
