Brussels to Karlsruhe Trains

Trip Overview

The train between Brussels and Karlsruhe takes 4h 25m. The train service runs several times per day from Brussels to Karlsruhe. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

4h 25m
Duration: 516 km
Distance: €111
Average price: Every 4 hours
Frequency

Train

best

Take the train from Brussels-Nord to Koeln Hbftrain Ice / ...
Take the train from Köln Hbf to Karlsruhe Hauptbahnhoftrain 43 / ...

4h 12m

€89–200

Brussels to Karlsruhe train times

Trains run every 4 hours between Brussels and Karlsruhe. The earliest departure is at 6:31 AM in the morning, and the last departure from Brussels is at 6:34 PM which arrives into Karlsruhe at 10:59 PM. All services require a transfer, and take on average 4h 25m. The schedules shown below are for the next available departures.

Departing Thursday, October 22, 2026

6:31 AM → 10:59 AM
4h 28m • 1 change
8:34 AM → 12:59 PM
4h 25m • 1 change
10:34 AM → 2:59 PM
4h 25m • 1 change
12:34 PM → 4:59 PM
4h 25m • 1 change
Show more

Departing Friday, October 23, 2026

6:31 AM → 10:59 AM
4h 28m • 1 change
8:34 AM → 12:59 PM
4h 25m • 1 change
10:34 AM → 2:59 PM
4h 25m • 1 change
12:34 PM → 4:59 PM
4h 25m • 1 change
Show more

Departing Saturday, October 24, 2026

6:31 AM → 10:59 AM
4h 28m • 1 change
8:34 AM → 12:59 PM
4h 25m • 1 change
10:34 AM → 2:59 PM
4h 25m • 1 change
12:34 PM → 4:59 PM
4h 25m • 1 change
Show more

Departing Sunday, October 25, 2026

6:31 AM → 10:59 AM
4h 28m • 1 change
8:34 AM → 12:59 PM
4h 25m • 1 change
10:34 AM → 2:59 PM
4h 25m • 1 change
12:34 PM → 4:59 PM
4h 25m • 1 change
Show more

Departing Monday, October 26, 2026

6:31 AM → 10:59 AM
4h 28m • 1 change
8:34 AM → 12:59 PM
4h 25m • 1 change
10:34 AM → 2:59 PM
4h 25m • 1 change
12:34 PM → 4:59 PM
4h 25m • 1 change
Show more

Departing Tuesday, October 27, 2026

6:31 AM → 10:59 AM
4h 28m • 1 change
8:34 AM → 12:59 PM
4h 25m • 1 change
10:34 AM → 2:59 PM
4h 25m • 1 change
12:34 PM → 4:59 PM
4h 25m • 1 change
Show more

Departing Wednesday, October 28, 2026

6:31 AM → 10:59 AM
4h 28m • 1 change
8:34 AM → 12:59 PM
4h 25m • 1 change
10:34 AM → 2:59 PM
4h 25m • 1 change
12:34 PM → 4:59 PM
4h 25m • 1 change
Show more

Frequently asked questions

Want to know about travelling from Brussels to Karlsruhe? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.