The average train between Brussels and La Défense takes 2h 13m and the fastest train takes 1h 42m. There is a train service every few hours from Brussels to La Défense. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run hourly between Brussels and La Défense. The earliest departure is at 6:02 AM in the morning, and the last departure from Brussels is at 9:29 PM which arrives into La Défense at 5:40 AM. All services require a transfer at Paris Nord and take an average of 2h 13m. The schedules shown below are for the next available departures.

2h 4m • 1 change

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2h 26m • 1 change

2h 19m • 1 change

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1h 52m • 1 change

2h 19m • 1 change

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2h 7m • 1 change

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2h 28m • 1 change

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2h 3m • 1 change
Want to know about travelling from Brussels to La Défense? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Brussels to La Défense. However, there are services departing from Brussels station and arriving at La Défense station via Paris Nord. The journey, including transfers, takes approximately 2h 13m.
Brussels to La Défense train services, operated by Eurostar, depart from Brussel-Zuid / Bruxelles-Midi station.
Brussels to La Défense train services, operated by Eurostar, arrive at Paris Nord station.
The distance between Brussels and La Défense is 265.1 km. The road distance is 319 km.
Eurostar operates a train from Brussel-Zuid / Bruxelles-Midi to Paris Nord every 20 minutes. Tickets cost €90–160 and the journey takes 1h 23m. Société Nationale des Chemins de fer Français (SNCF) also services this route every 4 hours.