Brussels to Mendrisio trains

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Trip Overview

The average train between Brussels and Mendrisio takes 12h 8m and the fastest train takes 8h 40m. The train service runs several times per day from Brussels to Mendrisio. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

12h 8m
Duration: 1,117 km
Distance: CHF 301
Average price: 3 times a day
Frequency

Train via Paris

best

Take the train from Brussel-Zuid / Bruxelles-Midi to Paris Nordtrain
Take the train from Paris Gare De Lyon to Zuerich Hbtrain Tgv
Take the train from Zürich HB to Luganotrain Ec / ...

9h 24m

CHF 212–423

Brussels to Mendrisio train times

Trains run 3 times a day between Brussels and Mendrisio. The earliest departure is at 7:42 AM in the morning, and the last departure from Brussels is at 10:13 PM which arrives into Mendrisio at 1:57 PM. All services require a transfer at Paris Nord and take an average of 12h 8m. The schedules shown below are for the next available departures.

Departing Wednesday, October 14, 2026

1:13 PM → 11:27 PM
10h 14m • 4 changes
3:16 PM → 8:57 AM
Arrives next day
17h 41m • 4 changes
9:16 PM → 1:57 PM
Arrives next day
16h 41m • 4 changes

Departing Thursday, October 15, 2026

8:13 AM → 5:18 PM
9h 5m • 4 changes
10:17 AM → 6:57 PM
8h 40m • 4 changes
1:13 PM → 11:27 PM
10h 14m • 4 changes
3:42 PM → 8:57 AM
Arrives next day
17h 15m • 4 changes
Show more

Departing Friday, October 16, 2026

8:13 AM → 5:18 PM
9h 5m • 4 changes
10:17 AM → 6:57 PM
8h 40m • 4 changes
1:13 PM → 11:27 PM
10h 14m • 4 changes
4:16 PM → 8:57 AM
Arrives next day
16h 41m • 4 changes

Departing Sunday, October 18, 2026

10:13 PM → 1:57 PM
Arrives next day
15h 44m • 4 changes

Departing Monday, October 19, 2026

7:42 AM → 4:57 PM
9h 15m • 4 changes
10:17 AM → 6:57 PM
8h 40m • 4 changes
1:13 PM → 11:27 PM
10h 14m • 4 changes
3:16 PM → 8:57 AM
Arrives next day
17h 41m • 4 changes
Show more

Departing Tuesday, October 20, 2026

7:42 AM → 4:57 PM
9h 15m • 4 changes
10:17 AM → 6:57 PM
8h 40m • 4 changes
1:13 PM → 11:27 PM
10h 14m • 4 changes

Frequently asked questions

Want to know about travelling from Brussels to Mendrisio? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Brussels to Mendrisio.

Launch map view

Distance: 1,116.7 km
Duration: 12h 8m

What companies run services between Brussels, Belgium and Mendrisio, Switzerland?

You can take a train from Brussel-Zuid / Bruxelles-Midi to Mendrisio via Paris Nord, Paris Gare De Lyon, Zuerich Hb, Zürich HB, and Lugano in around 9h 24m.

Operators