The average train between Brussels and Prague takes 13h 30m and the fastest train takes 11h 47m. The train service runs several times per day from Brussels to Prague. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run 5 times a day between Brussels and Prague. The earliest departure is at 6:31 AM in the morning, and the last departure from Brussels is at 8:34 PM which arrives into Prague at 12:21 PM. All services require a transfer at Frankfurt and take an average of 13h 30m. The schedules shown below are for the next available departures.



11h 50m • 3 changes


11h 47m • 3 changes


11h 48m • 3 changesArrives next day



15h 47m • 3 changes


11h 50m • 3 changes


11h 47m • 3 changes


11h 48m • 3 changesArrives next day



15h 47m • 3 changes


11h 50m • 3 changes


11h 47m • 3 changes


11h 48m • 3 changesArrives next day



15h 47m • 3 changes


11h 50m • 3 changes


11h 47m • 3 changes


11h 48m • 3 changesArrives next day



15h 47m • 3 changesWant to know about travelling from Brussels to Prague? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Brussels to Prague. However, there are services departing from Brussels-Nord station and arriving at Praha Hlavni Nadrazi station via Frankfurt(M) Flughafen Fernbf station, Nürnberg Hbf station and Schwandorf station. The journey, including transfers, takes approximately 13h 30m.
Brussels to Prague train services, operated by Deutsche Bahn Intercity (DB IC), depart from Brussels-Nord station.
Brussels to Prague train services, operated by Die Länderbahn, arrive at Praha Hlavni Nadrazi station.
Book your Brussels to Prague train tickets online with Omio.
The distance between Brussels and Prague is 717.3 km. The road distance is 863 km.
You can take a train from Brussels-Nord to Praha Hlavni Nadrazi via Frankfurt, Nürnberg Hbf, and Schwandorf in around 11h 32m.