The average train between Brussels and Rüsselsheim am Main takes 3h 6m and the fastest train takes 3h. The train service runs several times per day from Brussels to Rüsselsheim am Main. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run every 3 hours between Brussels and Rüsselsheim am Main. The earliest departure is at 6:31 AM in the morning, and the last departure from Brussels is at 8:34 PM which arrives into Rüsselsheim am Main at 12:42 AM. All services require a transfer at Frankfurt(M) Flughafen Fernbf and take an average of 3h 6m. The schedules shown below are for the next available departures.

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Want to know about travelling from Brussels to Rüsselsheim am Main? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Brussels to Rüsselsheim am Main. However, there are services departing from Brussels station and arriving at Rüsselsheim am Main station via Frankfurt(M) Flughafen Fernbf. The journey, including transfers, takes approximately 3h 6m.
Brussels to Rüsselsheim am Main train services, operated by Deutsche Bahn Intercity (DB IC), depart from Brussels-Nord station.
Brussels to Rüsselsheim am Main train services, operated by Deutsche Bahn Intercity (DB IC), arrive at Frankfurt(M) Flughafen Fernbf station.
Book your Brussels to Rüsselsheim am Main train tickets online with Deutsche Bahn Intercity (DB IC), Süwex and Deutsche Bahn Regio (DB Regional).
The distance between Brussels and Rüsselsheim am Main is 304 km. The road distance is 401 km.
Deutsche Bahn Intercity (DB IC) operates a train from Brussels-Nord to Frankfurt(M) Flughafen Fernbf hourly. Tickets cost €70–310 and the journey takes 2h 39m. Belgian Railways (NMBS/SNCB) also services this route once a week.