The average train between Brussels and Santa Margherita Ligure takes 16h 43m and the fastest train takes 12h 36m. The train service runs several times per day from Brussels to Santa Margherita Ligure. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run 3 times a day between Brussels and Santa Margherita Ligure. The earliest departure is at 6:51 AM in the morning, and the last departure from Brussels is at 9:29 PM which arrives into Santa Margherita Ligure at 5:01 PM. All services require a transfer at Paris Nord and take an average of 16h 43m. The schedules shown below are for the next available departures.





13h 27m • 5 changes
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17h 32m • 5 changes
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19h 32m • 5 changes





13h 27m • 5 changes
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17h 6m • 5 changes
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19h 33m • 5 changes





14h 2m • 5 changes
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13h 17m • 5 changes
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19h 50m • 5 changes
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17h 32m • 5 changes
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19h 32m • 5 changes
Want to know about travelling from Brussels to Santa Margherita Ligure? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Brussels to Santa Margherita Ligure. However, there are services departing from Brussels station and arriving at Santa Margherita Ligure station via Paris Nord. The journey, including transfers, takes approximately 16h 43m.
Brussels to Santa Margherita Ligure train services, operated by Eurostar, depart from Brussel-Zuid / Bruxelles-Midi station.
Brussels to Santa Margherita Ligure train services, operated by Eurostar, arrive at Genova Brignole station.
Book your Brussels to Santa Margherita Ligure train tickets online with Eurostar, Société Nationale des Chemins de fer Français (SNCF) and 3 other operators.
The distance between Brussels and Santa Margherita Ligure is 810.7 km. The road distance is 1,215 km.
You can take a train from Brussel-Zuid / Bruxelles-Midi to S.Margherita L.-Port via Paris Nord, Paris Gare De Lyon, Torino Porta Susa, Torino Lingotto, and Genova Brignole in around 11h 27m.