The average train between Brussels and Santes takes 1h 42m and the fastest train takes 1h 3m. The train service runs several times per day from Brussels to Santes. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run every 4 hours between Brussels and Santes. The earliest departure is at 6:27 AM in the morning, and the last departure from Brussels is at 6:09 PM which arrives into Santes at 7:35 PM. All services require a transfer at Lille Europe and take an average of 1h 42m. The schedules shown below are for the next available departures.


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1h 22m • 2 changes
Want to know about travelling from Brussels to Santes? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Brussels to Santes. However, there are services departing from Brussels station and arriving at Santes station via Lille Europe. The journey, including transfers, takes approximately 1h 42m.
Brussels to Santes train services, operated by TGV inOui, depart from Brussel-Zuid / Bruxelles-Midi station.
Brussels to Santes train services, operated by TGV inOui, arrive at Santes station.
Book your Brussels to Santes train tickets online with TGV inOui, Ilévia and Société Nationale des Chemins de fer Français (SNCF).
The distance between Brussels and Santes is 102 km. The road distance is 119 km.
You can take a train from Brussel-Zuid / Bruxelles-Midi to Santes via Lille Europe, Gare Lille Europe, Gare Lille Flandres, and Lille Flandres in around 1h 18m.