The average train between Brussels and Wiesbaden Hauptbahnhof takes 3h 46m and the fastest train takes 3h 39m. The train service runs several times per day from Brussels to Wiesbaden Hauptbahnhof. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run every 4 hours between Brussels and Wiesbaden Hauptbahnhof. The earliest departure is at 6:31 AM in the morning, and the last departure from Brussels is at 8:34 PM which arrives into Wiesbaden Hauptbahnhof at 12:43 AM. All services require a transfer at Frankfurt(M) Flughafen Fernbf and take an average of 3h 46m. The schedules shown below are for the next available departures.

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Want to know about travelling from Brussels to Wiesbaden Hauptbahnhof? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Brussels to Wiesbaden Hauptbahnhof. However, there are services departing from Brussels station and arriving at Wiesbaden Hauptbahnhof station via Frankfurt(M) Flughafen Fernbf. The journey, including transfers, takes approximately 3h 46m.
Brussels to Wiesbaden Hauptbahnhof train services, operated by Deutsche Bahn Intercity (DB IC), depart from Brussels-Nord station.
Brussels to Wiesbaden Hauptbahnhof train services, operated by Deutsche Bahn Intercity (DB IC), arrive at Frankfurt(M) Flughafen Fernbf station.
Book your Brussels to Wiesbaden Hauptbahnhof train tickets online with Deutsche Bahn Intercity (DB IC) and Deutsche Bahn Regio (DB Regional).
The distance between Brussels and Wiesbaden Hauptbahnhof is 288.9 km. The road distance is 420 km.
Deutsche Bahn Intercity (DB IC) operates a train from Brussels-Nord to Frankfurt(M) Flughafen Fernbf hourly. Tickets cost €70–300 and the journey takes 2h 39m. Belgian Railways (NMBS/SNCB) also services this route once a week.