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Buffalo to Framingham trains

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Trip Overview

The average train between Buffalo and Framingham takes 12h 31m and the fastest train takes 11h 46m. There is at least one train per day from Buffalo to Framingham. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

12h 31m
Duration
475 mi
Distance
$333
Average price
Once daily
Frequency

Buffalo to Framingham train times

Trains run once daily between Buffalo and Framingham. The earliest departure is at 7:12 AM in the morning, and the last departure from Buffalo is at 7:22 AM which arrives into Framingham at 7:58 PM. All services require a transfer, and take on average 12h 31m. The schedules shown below are for the next available departures.

Departing Friday, October 30, 2026

  •  → 

    AmtrakAmtrak12h 46m • 1 change

Departing Saturday, October 31, 2026

  •  → 

    AmtrakAmtrak12h 46m • 1 change

Departing Sunday, November 1, 2026

  •  → 

    AmtrakAmtrak11h 46m • 1 change

Departing Monday, November 2, 2026

  •  → 

    AmtrakAmtrak12h 36m • 1 change

Departing Tuesday, November 3, 2026

  •  → 

    AmtrakAmtrak12h 36m • 1 change

Departing Wednesday, November 4, 2026

  •  → 

    AmtrakAmtrak12h 36m • 1 change

Departing Thursday, November 5, 2026

  •  → 

    AmtrakAmtrak12h 36m • 1 change

Frequently asked questions

Want to know about travelling from Buffalo to Framingham? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Buffalo to Framingham.ExpandLaunch map view
  • Distance: 474.9 mi
  • Duration: 12h 31m

What companies run services between Buffalo, NY, USA and Framingham, MA, USA?

Amtrak operates a train from Buffalo Depew Station to Framingham Amtrak once daily. Tickets cost $250–400 and the journey takes 10h 53m.

Operators