The average train between Buffalo and Harrisburg, Pa takes 15h 6m and the fastest train takes 12h 13m. The train service runs several times per day from Buffalo to Harrisburg, Pa. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run 3 times a day between Buffalo and Harrisburg, Pa. The earliest departure is at 4:18 AM at night, and the last departure from Buffalo is at 12:15 PM which arrives into Harrisburg, Pa at 9:15 AM. All services require a transfer, and take on average 15h 6m. The schedules shown below are for the next available departures.

12h 17m • 1 change

12h 13m • 1 change
Arrives next day

22h 7m • 1 change

12h 14m • 1 change

13h 30m • 1 change
Arrives next day

22h 7m • 1 change

12h 14m • 1 change

13h 30m • 1 change
Arrives next day

21h • 1 change

12h 17m • 1 change

12h 13m • 1 change
Arrives next day

21h • 1 change
Want to know about travelling from Buffalo to Harrisburg, Pa? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Buffalo to Harrisburg, Pa. However, there are services departing from Buffalo station and arriving at Harrisburg, Pa station via Ny Moynihan Train Hall At Penn Station station. The journey, including transfers, takes approximately 15h 6m.
Buffalo to Harrisburg, Pa train services, operated by Amtrak, depart from Buffalo station.
Buffalo to Harrisburg, Pa train services, operated by Amtrak, arrive at Harrisburg station.
Book your Buffalo to Harrisburg, Pa train tickets online with Amtrak.
The distance between Buffalo and Harrisburg, Pa is 335.8 km. The road distance is 1,014 km.
You can take a train from Buffalo to Harrisburg via Ny Moynihan Train Hall At Penn Station in around 12h 40m.