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Buffalo to Illinois trains

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Trip Overview

The average train between Buffalo and Illinois takes 22h 52m and the fastest train takes 22h 47m. The train runs, on average, 6 times per week from Buffalo to Illinois. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

22h 52m
Duration
534 mi
Distance
$373
Average price
6 times a week
Frequency

Buffalo to Illinois train times

Trains run 6 times a week between Buffalo and Illinois. The earliest departure is at 12:15 PM in the afternoon, and the last departure from Buffalo is at 12:25 PM which arrives into Illinois at 10:12 AM. All services require a transfer, and take on average 22h 52m. The schedules shown below are for the next available departures.

Departing Friday, October 30, 2026

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    Arrives next day

    VIA RailAmtrak22h 57m • 1 change

Departing Saturday, October 31, 2026

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    Arrives next day

    VIA RailAmtrak22h 57m • 1 change

Departing Sunday, November 1, 2026

  •  → 

    Arrives next day

    VIA RailAmtrak22h 57m • 1 change

Departing Monday, November 2, 2026

  •  → 

    Arrives next day

    AmtrakAmtrak22h 47m • 1 change

Departing Tuesday, November 3, 2026

  •  → 

    Arrives next day

    AmtrakAmtrak22h 47m • 1 change

Departing Wednesday, November 4, 2026

  •  → 

    Arrives next day

    AmtrakAmtrak22h 47m • 1 change

Frequently asked questions

Want to know about travelling from Buffalo to Illinois? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Buffalo to Illinois.ExpandLaunch map view
  • Distance: 533.9 mi
  • Duration: 22h 52m

What companies run services between Buffalo, NY, USA and Illinois, USA?

Amtrak operates a train from Buffalo Depew Station to Chicago Union Station twice daily. Tickets cost $290–450 and the journey takes 10h 33m.

Operators