The train between Buffalo and La Crosse takes 28h 56m. The train runs, on average, 6 times per week from Buffalo to La Crosse. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run 6 times a week between Buffalo and La Crosse. The earliest departure is at 12:15 PM in the afternoon, and the last departure from Buffalo is at 12:15 PM which arrives into La Crosse at 4:11 PM. All services require a transfer at Buffalo Depew Station and take an average of 28h 56m. The schedules shown below are for the next available departures.
Want to know about travelling from Buffalo to La Crosse? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Buffalo to La Crosse. However, there are services departing from Buffalo station and arriving at La Crosse station via Chicago Union Station station. The journey, including transfers, takes approximately 28h 56m.
Buffalo to La Crosse train services, operated by VIA Rail, depart from Buffalo Depew Station.
Buffalo to La Crosse train services, operated by VIA Rail, arrive at La Crosse Amtrak Station.
Book your Buffalo to La Crosse train tickets online with VIA Rail and Amtrak.
The distance between Buffalo and La Crosse is 1,003.8 km. The road distance is 1,310 km.
You can take a train from Buffalo to La Crosse Amtrak Station via Buffalo Depew Station and Chicago Union Station in around 17h 49m.
