The average train between Buffalo and Medford takes 13h 52m and the fastest train takes 11h 48m. The train service runs several times per day from Buffalo to Medford. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run 3 times a day between Buffalo and Medford. The earliest departure is at 4:18 AM at night, and the last departure from Buffalo is at 12:15 PM which arrives into Medford at 7:36 AM. All services require a transfer at Ny Moynihan Train Hall At Penn Station and take an average of 13h 52m. The schedules shown below are for the next available departures.


11h 51m • 2 changes


12h 2m • 2 changes
Arrives next day


14h 38m • 2 changes


11h 51m • 2 changes


12h 2m • 2 changes
Arrives next day


19h 21m • 2 changes


11h 51m • 2 changes


12h 2m • 2 changes
Arrives next day


19h 21m • 2 changes
Want to know about travelling from Buffalo to Medford? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Buffalo to Medford. However, there are services departing from Buffalo station and arriving at Medford station via Ny Moynihan Train Hall At Penn Station station. The journey, including transfers, takes approximately 13h 52m.
Buffalo to Medford train services, operated by Amtrak, depart from Buffalo station.
Buffalo to Medford train services, operated by Amtrak, arrive at Ronkonkoma station.
The distance between Buffalo and Medford is 538.3 km. The road distance is 795 km.
You can take a train from Buffalo to Medford via Ny Moynihan Train Hall At Penn Station, New York Penn Station, and Ronkonkoma in around 10h 59m.