The average train between Buffalo and Parkesburg takes 14h 23m and the fastest train takes 11h 10m. The train service runs several times per day from Buffalo to Parkesburg. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run 3 times a day between Buffalo and Parkesburg. The earliest departure is at 4:18 AM at night, and the last departure from Buffalo is at 12:15 PM which arrives into Parkesburg at 9:43 AM. All services require a transfer, and take on average 14h 23m. The schedules shown below are for the next available departures.

11h 10m • 1 change

11h 13m • 1 change
Arrives next day

21h 28m • 1 change

11h 10m • 1 change

11h 13m • 1 change
Arrives next day

21h 9m • 1 change

11h 16m • 1 change

12h 32m • 1 change
Arrives next day

21h 9m • 1 change

11h 16m • 1 change

12h 32m • 1 change
Arrives next day

21h 28m • 1 change
Want to know about travelling from Buffalo to Parkesburg? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Buffalo to Parkesburg. However, there are services departing from Buffalo station and arriving at Parkesburg station via Ny Moynihan Train Hall At Penn Station station. The journey, including transfers, takes approximately 14h 23m.
Buffalo to Parkesburg train services, operated by Amtrak, depart from Buffalo station.
Buffalo to Parkesburg train services, operated by Amtrak, arrive at Parkesburg Station.
Book your Buffalo to Parkesburg train tickets online with Amtrak.
The distance between Buffalo and Parkesburg is 408.4 km. The road distance is 920 km.
You can take a train from Buffalo to Parkesburg Station via Ny Moynihan Train Hall At Penn Station in around 11h 40m.