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Buffalo to Pittsburgh trains

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Trip Overview

The average train between Buffalo and Pittsburgh takes 40h 58m and the fastest train takes 40h 40m. The train runs, on average, 5 times per week from Buffalo to Pittsburgh. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

40h 58m
Duration
332 mi
Distance
$243
Average price
5 times a week
Frequency

Buffalo to Pittsburgh train times

Trains run 5 times a week between Buffalo and Pittsburgh. The earliest departure is at 12:15 PM in the afternoon, and the last departure from Buffalo is at 12:25 PM which arrives into Pittsburgh at 5:05 AM. All services require a transfer at Buffalo Depew Station and take an average of 40h 58m. The schedules shown below are for the next available departures.

Departing Friday, October 30, 2026

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    Arrives +2 days

    VIA RailAmtrakAmtrak40h 50m • 2 changes

Departing Saturday, October 31, 2026

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    Arrives +2 days

    VIA RailAmtrakAmtrak41h 50m • 2 changes

Departing Sunday, November 1, 2026

  •  → 

    Arrives +2 days

    VIA RailAmtrakAmtrak40h 50m • 2 changes

Departing Monday, November 2, 2026

  •  → 

    Arrives +2 days

    AmtrakAmtrakAmtrak40h 40m • 2 changes

Departing Tuesday, November 3, 2026

  •  → 

    Arrives +2 days

    AmtrakAmtrakAmtrak40h 40m • 2 changes

Frequently asked questions

Want to know about travelling from Buffalo to Pittsburgh? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Buffalo to Pittsburgh.ExpandLaunch map view
  • Distance: 332.2 mi
  • Duration: 40h 58m

What companies run services between Buffalo, NY, USA and Pittsburgh, PA, USA?

You can take a train from Buffalo to Pittsburgh Amtrak Station via Buffalo Depew Station and Cleveland Amtrak in around 8h 42m.

Operators