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Buffalo to San Antonio trains

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Trip Overview

The train between Buffalo and San Antonio takes 2d 11h. The train runs, on average, 6 times per week from Buffalo to San Antonio. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

2d 11h
Duration
1,834 mi
Distance
$1,222
Average price
6 times a week
Frequency

Buffalo to San Antonio train times

Trains run 6 times a week between Buffalo and San Antonio. The service departs Buffalo at 12:25 PM in the afternoon, which arrives into San Antonio at 22:46:00. All services require a transfer at Buffalo Depew Station and take an average of 2d 11h. The schedules shown below are for the next available departures.

Departing Wednesday, November 11, 2026

  •  → 

    Arrives +2 days

    VIA RailAmtrakAmtrak2d 11h • 2 changes

Departing Thursday, November 12, 2026

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    Arrives +2 days

    VIA RailAmtrakAmtrak2d 11h • 2 changes

Departing Friday, November 13, 2026

  •  → 

    Arrives +2 days

    VIA RailAmtrakAmtrak2d 11h • 2 changes

Departing Saturday, November 14, 2026

  •  → 

    Arrives +2 days

    VIA RailAmtrakAmtrak2d 11h • 2 changes

Departing Sunday, November 15, 2026

  •  → 

    Arrives +2 days

    VIA RailAmtrakAmtrak2d 11h • 2 changes

Departing Monday, November 16, 2026

  •  → 

    Arrives +2 days

    VIA RailAmtrakAmtrak2d 11h • 2 changes

Frequently asked questions

Want to know about travelling from Buffalo to San Antonio? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Buffalo to San Antonio.ExpandLaunch map view
  • Distance: 1,834.3 mi
  • Duration: 2d 11h

What companies run services between Buffalo, NY, USA and San Antonio, TX, USA?

You can take a train from Buffalo to San Antonio Station via Buffalo Depew Station and Chicago Union Station in around 45h 26m.

Operators