The average train between Busto Arsizio and Rome takes 4h 36m and the fastest train takes 4h 3m. There is a train service every few hours from Busto Arsizio to Rome. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run hourly between Busto Arsizio and Rome. The earliest departure is at 5:51 AM in the morning, and the last departure from Busto Arsizio is at 11:51 PM which arrives into Rome at 9:19 AM. All services require a transfer, and take on average 4h 36m. The schedules shown below are for the next available departures.

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4h 4m • 1 changeWant to know about travelling from Busto Arsizio to Rome? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Busto Arsizio to Rome. However, there are services departing from Milano Centrale station and arriving at Roma Termini station via Roma Termini station. The journey, including transfers, takes approximately 4h 36m.
Busto Arsizio to Rome train services, operated by ItaloTreno, depart from Milano Centrale station.
Busto Arsizio to Rome train services, operated by ItaloTreno, arrive at Roma Termini station.
Book your Busto Arsizio to Rome train tickets online with Omio.
The distance between Busto Arsizio and Rome is 506 km. The road distance is 604 km.
ItaloTreno operates a train from Milano Centrale to Roma Termini every 30 minutes. Tickets cost €65–110 and the journey takes 3h 9m.