The average train between Cadenazzo and Rome takes 6h 17m and the fastest train takes 5h 26m. There is a train service every few hours from Cadenazzo to Rome. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run every 2 hours between Cadenazzo and Rome. The earliest departure is at 6:39 AM in the morning, and the last departure from Cadenazzo is at 8:39 PM which arrives into Rome at 9:25 AM. All services require a transfer, and take on average 6h 17m. The schedules shown below are for the next available departures.

5h 40m • 1 change

5h 56m • 1 change

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Want to know about travelling from Cadenazzo to Rome? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Cadenazzo to Rome. However, there are services departing from Cadenazzo station and arriving at Rome station via Milano Centrale. The journey, including transfers, takes approximately 6h 17m.
Cadenazzo to Rome train services, operated by Swiss Federal Railways (SBB CFF FFS), depart from Cadenazzo station.
Cadenazzo to Rome train services, operated by Swiss Federal Railways (SBB CFF FFS), arrive at Roma Termini station.
The distance between Cadenazzo and Rome is 551.3 km. The road distance is 679 km.
You can take a train from Cadenazzo to Roma Termini via Milano Centrale in around 4h 58m.