The average train between Calais and Domodossola takes 16h 42m and the fastest train takes 13h 4m. The train service runs several times per day from Calais to Domodossola. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run 3 times a day between Calais and Domodossola. The earliest departure is at 7:29 AM in the morning, and the last departure from Calais is at 8:29 PM which arrives into Domodossola at 4:10 PM. All services require a transfer at Lille Flandres and take an average of 16h 42m. The schedules shown below are for the next available departures.




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21h 41m • 4 changesWant to know about travelling from Calais to Domodossola? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Calais to Domodossola. However, there are services departing from Calais station and arriving at Domodossola station via Lille Flandres. The journey, including transfers, takes approximately 16h 42m.
Calais to Domodossola train services, operated by Société Nationale des Chemins de fer Français (SNCF), depart from Calais Ville station.
Calais to Domodossola train services, operated by Société Nationale des Chemins de fer Français (SNCF), arrive at Domodossola station.
Book your Calais to Domodossola train tickets online with Société Nationale des Chemins de fer Français (SNCF), TGV inOui and Swiss Federal Railways (SBB CFF FFS).
The distance between Calais and Domodossola is 716.2 km. The road distance is 1,074 km.
You can take a train from Calais Ville to Domodossola via Lille Flandres, Paris Nord, Paris Gare De Lyon, and Genève in around 10h 43m.