The average train between Cambridge and Port of Holyhead takes 5h 12m and the fastest train takes 5h 6m. The train service runs several times per day from Cambridge to Port of Holyhead. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run 5 times a day between Cambridge and Port of Holyhead. The earliest departure is at 6:42 AM in the morning, and the last departure from Cambridge is at 6:42 PM which arrives into Port of Holyhead at 11:53 PM. All services require a transfer at King's Cross and take an average of 5h 12m. The schedules shown below are for the next available departures.

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Want to know about travelling from Cambridge to Port of Holyhead? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Cambridge to Port of Holyhead. However, there are services departing from Cambridge station and arriving at Port of Holyhead station via King's Cross. The journey, including transfers, takes approximately 5h 12m.
Cambridge to Port of Holyhead train services, operated by Great Northern, depart from Cambridge station.
Cambridge to Port of Holyhead train services, operated by Great Northern, arrive at Holyhead station.
Book your Cambridge to Port of Holyhead train tickets online with Great Northern and Avanti West Coast.
The distance between Cambridge and Port of Holyhead is 342.3 km. The road distance is 513 km.
You can take a train from Cambridge to Port of Holyhead via King's Cross, London Euston, and Holyhead in around 6h 4m.