Rome2Rio

Cambridge to Chicago trains

Find Transport to Chicago

View schedule

Trip Overview

The train between Cambridge and Chicago takes 22h 15m. There is at least one train per day from Cambridge to Chicago. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

22h 15m
Duration
1,013 mi
Distance
$650
Average price
Once daily
Frequency

Cambridge to Chicago train times

Trains run once daily between Cambridge and Chicago. The service departs Cambridge at 12:57 PM in the afternoon, which arrives into Chicago at 10:12:00. All services run direct with no transfers required, and take on average 22h 15m. The schedules shown below are for the next available departures.

Departing Sunday, November 1, 2026

  •  → 

    Arrives next day

    train train 22h 15m • Direct

Departing Monday, November 2, 2026

  •  → 

    Arrives next day

    train train 22h 15m • Direct

Departing Tuesday, November 3, 2026

  •  → 

    Arrives next day

    train train 22h 15m • Direct

Departing Wednesday, November 4, 2026

  •  → 

    Arrives next day

    train train 22h 15m • Direct

Departing Thursday, November 5, 2026

  •  → 

    Arrives next day

    train train 22h 15m • Direct

Departing Friday, November 6, 2026

  •  → 

    Arrives next day

    train train 22h 15m • Direct

Departing Saturday, November 7, 2026

  •  → 

    Arrives next day

    train train 22h 15m • Direct

Frequently asked questions

Want to know about travelling from Cambridge to Chicago? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Cambridge to Chicago.ExpandLaunch map view
  • Distance: 1,013.2 mi
  • Duration: 22h 15m

What companies run services between Cambridge, MA, USA and Chicago, IL, USA?

Amtrak operates a train from Boston to Chicago Union Station once daily. Tickets cost $550–900 and the journey takes 22h 15m.

Operators