The average train between Cambridge and Poughkeepsie takes 6h 43m and the fastest train takes 5h 18m. There is a train service every few hours from Cambridge to Poughkeepsie. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run every 2 hours between Cambridge and Poughkeepsie. The earliest departure is at 5:05 AM in the morning, and the last departure from Cambridge is at 8:00 PM which arrives into Poughkeepsie at 8:43 AM. All services require a transfer, and take on average 6h 43m. The schedules shown below are for the next available departures.

5h 40m • 1 change

6h 16m • 1 change

5h 18m • 1 change

6h 22m • 1 change

5h 25m • 1 change

5h 24m • 1 change

5h 57m • 1 change

5h 22m • 1 change

5h 54m • 1 change

5h 24m • 1 change

5h 57m • 1 change

5h 22m • 1 change

6h 38m • 1 change

5h 40m • 1 change

5h 40m • 1 change

6h 16m • 1 change

6h 38m • 1 change

5h 40m • 1 change

5h 40m • 1 change

6h 16m • 1 change
Want to know about travelling from Cambridge to Poughkeepsie? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Cambridge to Poughkeepsie. However, there are services departing from Cambridge station and arriving at Poughkeepsie station via Ny Moynihan Train Hall At Penn Station station. The journey, including transfers, takes approximately 6h 43m.
Cambridge to Poughkeepsie train services, operated by Amtrak Acela, depart from Boston station.
Cambridge to Poughkeepsie train services, operated by Amtrak Acela, arrive at Poughkeepsie Amtrak Station.
Book your Cambridge to Poughkeepsie train tickets online with Amtrak Acela and Amtrak.
The distance between Cambridge and Poughkeepsie is 244.3 km. The road distance is 487 km.
You can take a train from Boston to Poughkeepsie Amtrak Station via Ny Moynihan Train Hall At Penn Station in around 6h 17m.