The average train between Carluke and Prestwick takes 1h 53m and the fastest train takes 1h 24m. There is an hourly train service from Carluke to Prestwick. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run hourly between Carluke and Prestwick. The earliest departure is at 5:58 AM in the morning, and the last departure from Carluke is at 11:31 PM which arrives into Prestwick at 6:46 AM. All services require a transfer, and take on average 1h 53m. The schedules shown below are for the next available departures.

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1h 45m • 1 changeWant to know about travelling from Carluke to Prestwick? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Carluke to Prestwick. However, there are services departing from Carluke station and arriving at Prestwick Town station via Glasgow Central station. The journey, including transfers, takes approximately 1h 53m.
Carluke to Prestwick train services, operated by ScotRail, depart from Carluke station.
Carluke to Prestwick train services, operated by ScotRail, arrive at Prestwick Town station.
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The distance between Carluke and Prestwick is 55.2 km. The road distance is 66 km.
You can take a train from Carluke to Prestwick Town via Glasgow Central in around 1h 43m.