The average train between Cartagena and Madrid takes 5h 18m and the fastest train takes 4h 2m. The train service runs several times per day from Cartagena to Madrid. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run 4 times a day between Cartagena and Madrid. The earliest departure is at 5:09 AM in the morning, and the last departure from Cartagena is at 9:35 PM which arrives into Madrid at 10:23 AM. All services require a transfer, and take on average 5h 18m. The schedules shown below are for the next available departures.

4h 2m • 1 change

5h 8m • 1 change

4h 43m • 1 change

6h 7m • 1 change

4h 2m • 1 change

5h 8m • 1 change

4h 43m • 1 change

6h 7m • 1 change

4h 2m • 1 change

5h 8m • 1 change

4h 43m • 1 change

6h 7m • 1 change
Want to know about travelling from Cartagena to Madrid? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Cartagena to Madrid. However, there are services departing from Cartagena station and arriving at Madrid station via Murcia Del Carmen. The journey, including transfers, takes approximately 5h 18m.
Cartagena to Madrid train services, operated by Renfe Viajeros, depart from Cartagena station.
Cartagena to Madrid train services, operated by Renfe Viajeros, arrive at Madrid Chamartín station.
Book your Cartagena to Madrid train tickets online with Renfe Viajeros, Renfe AVE and Ouigo.
The distance between Cartagena and Madrid is 390.9 km. The road distance is 559 km.
You can take a train from Cartagena to Madrid Chamartín via Murcia Del Carmen in around 5h 7m.