The average train between Casale Monferrato and Mendrisio takes 3h 39m and the fastest train takes 2h 50m. The train service runs several times per day from Casale Monferrato to Mendrisio. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run 5 times a day between Casale Monferrato and Mendrisio. The earliest departure is at 6:05 AM in the morning, and the last departure from Casale Monferrato is at 8:31 PM which arrives into Mendrisio at 11:42 PM. All services require a transfer at Mortara and take an average of 3h 39m. The schedules shown below are for the next available departures.



3h 40m • 3 changes



3h 51m • 3 changes



3h 51m • 3 changes



4h 21m • 3 changes



3h 40m • 3 changes



3h 51m • 3 changes



3h 51m • 3 changes



4h 21m • 3 changes



3h 40m • 3 changes



3h 51m • 3 changes



3h 51m • 3 changes



4h 21m • 3 changes



3h 40m • 3 changes



3h 51m • 3 changes



3h 51m • 3 changes



4h 21m • 3 changes
Want to know about travelling from Casale Monferrato to Mendrisio? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Casale Monferrato to Mendrisio. However, there are services departing from Casale Monferrato station and arriving at Mendrisio station via Mortara. The journey, including transfers, takes approximately 3h 39m.
Casale Monferrato to Mendrisio train services, operated by Trenitalia, depart from Casale Monferrato station.
Casale Monferrato to Mendrisio train services, operated by Trenitalia, arrive at Mendrisio station.
The distance between Casale Monferrato and Mendrisio is 92 km. The road distance is 135 km.
You can take a train from Casale Monferrato to Mendrisio via Mortara, Milano Romolo, Romolo, Centrale Fs, and Milano Centrale in around 3h 50m.