Cassino to Brindisi Trains

Cassino to Brindisi trains

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Trip Overview

The average train between Cassino and Brindisi takes 6h 26m and the fastest train takes 6h 5m. The train service runs several times per day from Cassino to Brindisi. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

6h 26m
Duration: 469 km
Distance: €76
Average price: 3 times a day
Frequency

Train (Trenitalia)

best

Take the train from Cassino to Casertatrain Re
Take the train from Caserta to Brindisitrain Fr / ...

6h 38m

€58–110

Cassino to Brindisi train times

Trains run 3 times a day between Cassino and Brindisi. The earliest departure is at 6:44 AM in the morning, and the last departure from Cassino is at 4:51 PM which arrives into Brindisi at 11:20 PM. All services require a transfer, and take on average 6h 26m. The schedules shown below are for the next available departures.

Departing Monday, October 26, 2026

6:44 AM → 1:54 PM
7h 10m • 1 change
9:12 AM → 3:28 PM
6h 16m • 1 change
2:06 PM → 8:20 PM
6h 14m • 1 change
3:15 PM → 9:20 PM
6h 5m • 1 change
Show more

Departing Tuesday, October 27, 2026

6:44 AM → 1:54 PM
7h 10m • 1 change
9:12 AM → 3:28 PM
6h 16m • 1 change
2:06 PM → 8:20 PM
6h 14m • 1 change
3:15 PM → 9:20 PM
6h 5m • 1 change
Show more

Departing Wednesday, October 28, 2026

6:44 AM → 1:54 PM
7h 10m • 1 change
9:12 AM → 3:28 PM
6h 16m • 1 change
2:06 PM → 8:20 PM
6h 14m • 1 change
3:15 PM → 9:20 PM
6h 5m • 1 change
Show more

Departing Thursday, October 29, 2026

6:44 AM → 1:54 PM
7h 10m • 1 change
9:12 AM → 3:28 PM
6h 16m • 1 change
2:06 PM → 8:20 PM
6h 14m • 1 change
3:15 PM → 9:20 PM
6h 5m • 1 change
Show more

Frequently asked questions

Want to know about travelling from Cassino to Brindisi? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.