The average train between Cassino and Perugia takes 5h 33m and the fastest train takes 4h 46m. The train service runs several times per day from Cassino to Perugia. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run 5 times a day between Cassino and Perugia. The earliest departure is at 3:38 AM at night, and the last departure from Cassino is at 4:20 PM which arrives into Perugia at 9:37 PM. All services require a transfer, and take on average 5h 33m. The schedules shown below are for the next available departures.

5h 7m • 1 change

4h 46m • 1 change

6h 40m • 1 change

4h 52m • 1 change

6h 1m • 1 change

4h 59m • 1 change

6h 31m • 1 change

5h • 1 change

6h 1m • 1 change

4h 59m • 1 change

6h 31m • 1 change

5h • 1 change

6h 1m • 1 change

4h 59m • 1 change

6h 31m • 1 change

5h • 1 change

6h 1m • 1 change

4h 59m • 1 change

6h 31m • 1 change

5h • 1 change

6h 1m • 1 change

4h 59m • 1 change

6h 31m • 1 change

5h • 1 change
Want to know about travelling from Cassino to Perugia? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Cassino to Perugia. However, there are services departing from Cassino station and arriving at Perugia station via Roma Termini. The journey, including transfers, takes approximately 5h 33m.
Cassino to Perugia train services, operated by Trenitalia, depart from Cassino station.
Cassino to Perugia train services, operated by Trenitalia, arrive at Perugia station.
Book your Cassino to Perugia train tickets online with Trenitalia and Trenitalia Frecce.
The distance between Cassino and Perugia is 216.1 km. The road distance is 326 km.
You can take a train from Cassino to Perugia via Roma Termini in around 5h 38m.