The average train between Central London and Manchester takes 2h 52m and the fastest train takes 2h 44m. The train runs at least 2 times per hour from Central London to Manchester. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run every 30 minutes between Central London and Manchester. The earliest departure is at 5:25 AM in the morning, and the last departure from Central London is at 9:22 PM which arrives into Manchester at 12:39 AM. All services require a transfer at Russell Square station and take an average of 2h 52m. The schedules shown below are for the next available departures.

3h • 1 change

3h 1m • 1 change

3h 2m • 1 change

2h 47m • 1 change
Want to know about travelling from Central London to Manchester? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Central London to Manchester. However, there are services departing from Central London station and arriving at Manchester station via Manchester Piccadilly. The journey, including transfers, takes approximately 2h 52m.
Central London to Manchester train services, operated by London Underground (Tube), depart from London Euston station.
Central London to Manchester train services, operated by London Underground (Tube), arrive at Manchester Piccadilly station.
The distance between Central London and Manchester is 256.8 km. The road distance is 311 km.
Avanti West Coast operates a train from London Euston to Manchester Piccadilly every 30 minutes. Tickets cost £65–110 and the journey takes 2h 12m.