The average train between Cesena and Brindisi takes 6h 55m and the fastest train takes 6h 25m. The train service runs several times per day from Cesena to Brindisi. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run 5 times a day between Cesena and Brindisi. The earliest departure is at 8:51 AM in the morning, and the last departure from Cesena is at 5:04 PM which arrives into Brindisi at 11:29 PM. All services require a transfer, and take on average 6h 55m. The schedules shown below are for the next available departures.

6h 51m • 1 change

7h 32m • 1 change

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6h 38m • 1 change

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7h 32m • 1 change

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6h 38m • 1 change

6h 51m • 1 change

7h 32m • 1 change

7h 10m • 1 change

6h 38m • 1 change

6h 51m • 1 change

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6h 38m • 1 change

6h 51m • 1 change

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6h 38m • 1 change
Want to know about travelling from Cesena to Brindisi? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Cesena to Brindisi. However, there are services departing from Cesena station and arriving at Brindisi station via Brindisi. The journey, including transfers, takes approximately 6h 55m.
Cesena to Brindisi train services, operated by Trenitalia Intercity, depart from Rimini station.
Cesena to Brindisi train services, operated by Trenitalia Intercity, arrive at Brindisi station.
Book your Cesena to Brindisi train tickets online with Trenitalia Intercity, Trenitalia Frecce and Deutsche Bahn Intercity (DB IC).
The distance between Cesena and Brindisi is 608.6 km. The road distance is 673 km.
Trenitalia Frecce operates a train from Rimini to Brindisi hourly. Tickets cost €95–190 and the journey takes 5h 56m. Trenitalia Intercity also services this route every 3 hours.