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Chicago to Greenville Station trains

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Trip Overview

The train between Chicago and Greenville Station takes 34h 29m. The train runs, on average, 2 times per week from Chicago to Greenville Station. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

34h 29m
Duration
1,173 mi
Distance
$343
Average price
Twice a week
Frequency

Chicago to Greenville Station train times

Trains run twice a week between Chicago and Greenville Station. The earliest departure is at 5:55 PM in the evening, and the last departure from Chicago is at 5:55 PM which arrives into Greenville Station at 5:24 AM. All services require a transfer, and take on average 34h 29m. The schedules shown below are for the next available departures.

Departing Saturday, October 10, 2026

  •  → 

    Arrives +2 days

    AmtrakAmtrak34h 29m • 1 change

Departing Tuesday, October 13, 2026

  •  → 

    Arrives +2 days

    AmtrakAmtrak34h 29m • 1 change

Frequently asked questions

Want to know about travelling from Chicago to Greenville Station? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Chicago to Greenville Station.ExpandLaunch map view
  • Distance: 1,172.6 mi
  • Duration: 34h 29m

What companies run services between Chicago, IL, USA and Greenville Station, SC, USA?

You can take a train from Chicago Union Station to Greenville Amtrak Station via Charlottesville in around 30h 12m.

Operators