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Chicago to Natick trains

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Trip Overview

The average train between Chicago and Natick takes 22h 26m and the fastest train takes 22h 14m. The train runs, on average, 6 times per week from Chicago to Natick. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

22h 26m
Duration
997 mi
Distance
$649
Average price
6 times a week
Frequency

Chicago to Natick train times

Trains run 6 times a week between Chicago and Natick. The service departs Chicago at 9:30 PM at night, which arrives into Natick at 21:59:00. All services require a transfer, and take on average 22h 26m. The schedules shown below are for the next available departures.

Departing Friday, October 30, 2026

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    Arrives next day

    AmtrakMBTA23h 29m • 1 change

Departing Saturday, October 31, 2026

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    Arrives next day

    AmtrakMBTA22h 14m • 1 change

Departing Sunday, November 1, 2026

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    Arrives next day

    AmtrakMBTA22h 14m • 1 change

Departing Monday, November 2, 2026

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    Arrives next day

    AmtrakMBTA22h 14m • 1 change

Departing Tuesday, November 3, 2026

  •  → 

    Arrives next day

    AmtrakMBTA22h 14m • 1 change

Departing Wednesday, November 4, 2026

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    Arrives next day

    AmtrakMBTA22h 14m • 1 change

Frequently asked questions

Want to know about travelling from Chicago to Natick? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Chicago to Natick.ExpandLaunch map view
  • Distance: 996.9 mi
  • Duration: 22h 26m

What companies run services between Chicago, IL, USA and Natick, MA, USA?

Amtrak operates a train from Chicago Union Station to Framingham Amtrak once daily. Tickets cost $500–850 and the journey takes 21h 28m.

Operators