The average train between Chiusi and Brindisi takes 9h 15m and the fastest train takes 8h 25m. The train service runs several times per day from Chiusi to Brindisi. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run 3 times a day between Chiusi and Brindisi. The earliest departure is at 5:25 AM in the morning, and the last departure from Chiusi is at 10:59 PM which arrives into Brindisi at 1:57 PM. All services require a transfer, and take on average 9h 15m. The schedules shown below are for the next available departures.

8h 32m • 1 change

9h 1m • 1 change

8h 50m • 1 change

8h 25m • 1 change
Want to know about travelling from Chiusi to Brindisi? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Chiusi to Brindisi. However, there are services departing from Chiusi station and arriving at Brindisi station via Roma Termini. The journey, including transfers, takes approximately 9h 15m.
Chiusi to Brindisi train services, operated by Trenitalia Intercity, depart from Chiusi-Chianciano T. station.
Chiusi to Brindisi train services, operated by Trenitalia Intercity, arrive at Brindisi station.
Book your Chiusi to Brindisi train tickets online with Trenitalia Intercity, Trenitalia Frecce and Trenitalia.
The distance between Chiusi and Brindisi is 562.4 km. The road distance is 738 km.
You can take a train from Chiusi-Chianciano T. to Brindisi via Roma Termini in around 8h 27m.