The average train between Colosseum and Piazza del Duomo takes 3h 48m and the fastest train takes 3h 20m. There is a train service every few hours from Colosseum to Piazza del Duomo. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run hourly between Colosseum and Piazza del Duomo. The earliest departure is at 1:50 AM at night, and the last departure from Colosseum is at 11:49 PM which arrives into Piazza del Duomo at 9:30 AM. All services require a transfer at Colosseo and take an average of 3h 48m. The schedules shown below are for the next available departures.


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3h 28m • 2 changesWant to know about travelling from Colosseum to Piazza del Duomo? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Colosseum to Piazza del Duomo. However, there are services departing from Roma Termini station and arriving at Milano Centrale station via Milano Centrale station. The journey, including transfers, takes approximately 3h 48m.
Colosseum to Piazza del Duomo train services, operated by ItaloTreno, depart from Roma Termini station.
Colosseum to Piazza del Duomo train services, operated by ItaloTreno, arrive at Milano Centrale station.
The distance between Colosseum and Piazza del Duomo is 477.9 km. The road distance is 574 km.
ItaloTreno operates a train from Roma Termini to Milano Centrale every 30 minutes. Tickets cost €65–120 and the journey takes 3h 5m.