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Columbia to St. Louis trains

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Trip Overview

The train between Columbia and St. Louis takes 35h 29m. The train runs, on average, 6 times per week from Columbia to St. Louis. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

35h 29m
Duration
1,553 mi
Distance
$1,008
Average price
6 times a week
Frequency

Columbia to St. Louis train times

Trains run 6 times a week between Columbia and St. Louis. The service departs Columbia at 4:22 AM at night, which arrives into St. Louis at 14:51:00. All services require a transfer, and take on average 35h 29m. The schedules shown below are for the next available departures.

Departing Friday, November 6, 2026

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    Arrives next day

    AmtrakAmtrak35h 29m • 1 change

Departing Saturday, November 7, 2026

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    Arrives next day

    AmtrakAmtrak35h 29m • 1 change

Departing Sunday, November 8, 2026

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    Arrives next day

    AmtrakAmtrak35h 29m • 1 change

Departing Monday, November 9, 2026

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    Arrives next day

    AmtrakAmtrak35h 29m • 1 change

Departing Tuesday, November 10, 2026

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    Arrives next day

    AmtrakAmtrak35h 29m • 1 change

Departing Wednesday, November 11, 2026

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    Arrives next day

    AmtrakAmtrak35h 29m • 1 change

Frequently asked questions

Want to know about travelling from Columbia to St. Louis? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Columbia to St. Louis.ExpandLaunch map view
  • Distance: 1,552.5 mi
  • Duration: 35h 29m

What companies run services between Columbia, SC, USA and St. Louis, MO, USA?

You can take a train from Columbia Station to St. Louis via Chicago Union Station in around 35h 9m.

Operators