The average train between Como and Santa Maria Novella takes 3h 51m and the fastest train takes 3h 28m. There is a train service every few hours from Como to Santa Maria Novella. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run hourly between Como and Santa Maria Novella. The earliest departure is at 4:36 AM at night, and the last departure from Como is at 9:36 PM which arrives into Santa Maria Novella at 7:04 AM. All services require a transfer at Milano Centrale and take an average of 3h 51m. The schedules shown below are for the next available departures.

3h 28m • 1 change

3h 45m • 1 change

3h 28m • 1 change

3h 28m • 1 change

3h 28m • 1 change

3h 45m • 1 change

3h 28m • 1 change

3h 28m • 1 change

3h 28m • 1 change

3h 45m • 1 change

3h 28m • 1 change

3h 28m • 1 change
Want to know about travelling from Como to Santa Maria Novella? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Como to Santa Maria Novella. However, there are services departing from Como station and arriving at Santa Maria Novella station via Milano Centrale. The journey, including transfers, takes approximately 3h 51m.
Como to Santa Maria Novella train services, operated by Swiss Federal Railways (SBB CFF FFS), depart from Como S. Giovanni station.
Como to Santa Maria Novella train services, operated by Swiss Federal Railways (SBB CFF FFS), arrive at Firenze S.M.N. station.
Book your Como to Santa Maria Novella train tickets online with Swiss Federal Railways (SBB CFF FFS) and Trenitalia Frecce.
The distance between Como and Santa Maria Novella is 283.5 km. The road distance is 351 km.
You can take a train from Como S. Giovanni to Santa Maria Novella via Milano Centrale and Firenze S.M.N. in around 2h 59m.