The average train between Como and Vatican Museums takes 4h 56m and the fastest train takes 4h 37m. There is a train service every few hours from Como to Vatican Museums. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run hourly between Como and Vatican Museums. The earliest departure is at 4:36 AM at night, and the last departure from Como is at 6:36 PM which arrives into Vatican Museums at 11:40 PM. All services require a transfer at Milano Centrale and take an average of 4h 56m. The schedules shown below are for the next available departures.


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4h 40m • 2 changes

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4h 37m • 2 changes

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5h 1m • 2 changes

4h 38m • 2 changes

4h 58m • 2 changesWant to know about travelling from Como to Vatican Museums? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Como to Vatican Museums. However, there are services departing from Como station and arriving at Vatican Museums station via Milano Centrale. The journey, including transfers, takes approximately 4h 56m.
Como to Vatican Museums train services, operated by Swiss Federal Railways (SBB CFF FFS), depart from Como S. Giovanni station.
Como to Vatican Museums train services, operated by Swiss Federal Railways (SBB CFF FFS), arrive at Roma Termini station.
The distance between Como and Vatican Museums is 511.2 km. The road distance is 632 km.
You can take a train from Como S. Giovanni to Vatican Museums via Milano Centrale, Roma Termini, Termini, and Ottaviano in around 4h 17m.