The average train between Düsseldorf and Enschede takes 3h 6m and the fastest train takes 2h 49m. There is a train service every few hours from Düsseldorf to Enschede. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run hourly between Düsseldorf and Enschede. The earliest departure is at 2:44 AM at night, and the last departure from Düsseldorf is at 9:06 PM which arrives into Enschede at 12:27 AM. All services require a transfer, and take on average 3h 6m. The schedules shown below are for the next available departures.

2h 53m • 1 change

2h 53m • 1 change

3h 15m • 1 change

2h 53m • 1 change

3h • 1 change

2h 49m • 1 change

2h 53m • 1 change

2h 53m • 1 change

3h 36m • 1 change

3h 1m • 1 change

2h 49m • 1 change

2h 53m • 1 change
Want to know about travelling from Düsseldorf to Enschede? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Düsseldorf to Enschede. However, there are services departing from Düsseldorf station and arriving at Enschede station via Münster Hauptbahnhof. The journey, including transfers, takes approximately 3h 6m.
Düsseldorf to Enschede train services, operated by Deutsche Bahn Intercity (DB IC), depart from Düsseldorf Hbf station.
Düsseldorf to Enschede train services, operated by Deutsche Bahn Intercity (DB IC), arrive at Enschede station.
Book your Düsseldorf to Enschede train tickets online with Deutsche Bahn Intercity (DB IC) and Deutsche Bahn Regio (DB Regional).
The distance between Düsseldorf and Enschede is 111.1 km. The road distance is 187 km.
You can take a train from Düsseldorf Hbf to Enschede via Münster Hauptbahnhof in around 3h 13m.