The average train between Düsseldorf and Mainz takes 2h 2m and the fastest train takes 1h 37m. There is a train service every few hours from Düsseldorf to Mainz. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run hourly between Düsseldorf and Mainz. The earliest departure is at 4:58 AM at night, and the last departure from Düsseldorf is at 11:38 PM which arrives into Mainz at 2:52 AM. All services require a transfer, and take on average 2h 2m. The schedules shown below are for the next available departures.

2h 17m • 1 change

2h 1m • 1 change

1h 38m • 1 change

1h 51m • 1 change

2h 24m • 1 change

1h 38m • 1 change

2h • 1 change

1h 38m • 1 change

2h 24m • 1 change

1h 38m • 1 change

2h • 1 change

1h 38m • 1 change
Want to know about travelling from Düsseldorf to Mainz? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Düsseldorf to Mainz. However, there are services departing from Düsseldorf station and arriving at Mainz station via Frankfurt. The journey, including transfers, takes approximately 2h 2m.
Düsseldorf to Mainz train services, operated by Deutsche Bahn Intercity (DB IC), depart from Düsseldorf Hbf station.
Düsseldorf to Mainz train services, operated by Deutsche Bahn Intercity (DB IC), arrive at Mainz, Römisches Theater station.
Book your Düsseldorf to Mainz train tickets online with Deutsche Bahn Intercity (DB IC), vlexx and 2 other operators.
The distance between Düsseldorf and Mainz is 173.7 km. The road distance is 232 km.
You can take a train from Düsseldorf Hbf to Mainz, Römisches Theater via Frankfurt in around 1h 53m.